Prisma Health Expands Hiring Across Regions
On Oct 14, 2026, Prisma Health posted 135 new job openings across Columbia, Greenville and other SC locations.
Prisma Health announced a major hiring push on October 14, 2026, adding 135 open positions across its Midlands and Upstate footprint, including Columbia, Greenville, Easley, Seneca and Laurens, as well as select sites in Tennessee. Roles span clinical and support staff, from nurse practitioners and physician assistants to radiology technicians, medical assistants, phlebotomists and registered nurses.
Openings cover hospital and ambulatory settings, with opportunities in specialties such as urology, ophthalmology, orthopedics, pediatrics and critical care, as well as administrative and patient services roles.
The drive reflects ongoing service expansion and a continued effort to recruit for a diverse range of shifts, including full-time, part-time and PRN positions across day, evening and night schedules.

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