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UMass Amherst

\- Work on developing novel therapeutics for the treatment of pediatric brain tumors at the Sirianni Laboratory of Nanomedicine.
\- Develop polymeric (PLA-PEG) drug-loaded nanoparticles for enhanced drug delivery efficacy in treating central nervous system diseases.
\- Assist in formulation and labeling processes of polymeric nanoparticles, employing techniques such as centrifugation, micro pipetting, dynamic light scattering, fluorescence, and absorbance assays, ensuring optimized drug loading and controlled release characteristics.

Research Intern

\- Conducted statistical analysis of Flow Cytometry data for CAR-T Cell Killing Potency assay using FlowJo and GraphPad Prism.
\- Performed comprehensive literature reviews on 10+ articles to identify GMP-friendly cytotoxicity assays (e.g., Luciferase, xCELLigence impedance).
\- Presented an economic suggestion for selecting GMP-friendly methods to enhance method performance at CRISPR.
\- Independently authored 2 protocols for Flow Cytometry and GraphPad Prism analysis.
\- Routinely collaborated with a team of 5 to record concise and informative meeting minutes.

Proposal Report for CRIPSR Therapeutics.pdf

Analytical Development Intern

\- Conducted literature reviews of 5+ articles to assess the efficacy of pharmacological agents for adhesion prevention to develop a sprayable hydrogel-based anti-postoperative adhesion barrier.
\- Applied concepts from organic and materials chemistry for the development of the healing barriers.
\- Collaborated with a multidisciplinary team to understand tissue/cell-material interactions.
\- Delivered an end-semester research presentation on advancements in adhesion-blocking strategies, highlighting the use of different biomaterial-based membranes and nano-drug delivery systems.

Student Research Assistant

\- Ensured seamless move-in process for residents through personal room visits, establishing trust, and addressing concerns.
\- Provided timely support to residents, handling inquiries, and assisting with practical tasks like laundry and mail operations.
\- Assumed critical weekend duty, coordinating emergency situations as needed, while maintaining composure under pressure.
\- Maintained strict adherence to protocols, documenting all emergency situations, ensuring compliance with university policies.
\- Cultivated community and camaraderie through floor-wide social events, fostering meaningful connections and enhancing residential experience.

Resident Assistant

\- Meet with the interim Dean of the College of Natural Sciences (CNS) 3-4 times a semester to discuss and provide feedback on current and future CNS plans and proposals.
\- Serve as a liaison between students and the department, ensuring communication of student experiences and needs.
\- Contribute to the development of improved policies and practices that enhance the college experience for current and future students.

Nairita Guha

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